⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793365 | 0.84 | — | — | |
| SCHEMBL28325990 | 0.80 | — | — | |
| SCHEMBL297600 | 0.79 | CES2 (0.31) | — | |
| SCHEMBL2468774 | 0.77 | CES2 (0.33) | — | |
| SCHEMBL296133 | 0.76 | CES2 (0.32) | — | |
| SCHEMBL10769963 | 0.75 | — | — | |
| SCHEMBL6910240 | 0.74 | — | — | |
| SCHEMBL962974 | 0.74 | CES2 (0.33) | — | |
| SCHEMBL7256155 | 0.73 | CES2 (0.39) | — | |
| SCHEMBL871697 | 0.73 | CES2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0990668-B1 | Optically transparent hydrogels and processes for their production | JOHNSON & JOHNSON VISION PROD (US) | 2002-11-27 | — | — | EP | disclosed |
| EP-0990668-A1 | Optically transparent hydrogels and processes for their production | JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) | 2000-04-05 | — | — | EP | disclosed |