Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.53 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.53 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 4/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7629312 | 1.00 | SLC10A2 (0.53) | SLC10A2SLC10A1SLC10A6ALDH1A1KMT2A | |
| SCHEMBL6861189 | 0.81 | KMT2A (0.60) | SLC10A2SLC10A1SLC10A6ALDH1A1KMT2A | |
| SCHEMBL6861188 | 0.81 | KMT2A (0.60) | SLC10A2SLC10A1SLC10A6ALDH1A1KMT2A | |
| SCHEMBL7120319 | 0.80 | SLC10A6 (0.76) | SLC10A2SLC10A1SLC10A6ALDH1A1KMT2A | |
| SCHEMBL7209334 | 0.77 | SMO (0.53) | ALDH1A1KMT2AMEN1POLBHSD17B10 | |
| SCHEMBL7209329 | 0.77 | SMO (0.53) | ALDH1A1KMT2AMEN1POLBHSD17B10 | |
| SCHEMBL7213156 | 0.77 | SLC10A2 (0.55) | SLC10A2SLC10A1SLC10A6ALDH1A1KMT2A | |
| SCHEMBL7117439 | 0.76 | SLC10A2 (0.63) | SLC10A2SLC10A1SLC10A6ALDH1A1KMT2A | |
| SCHEMBL5926665 | 0.76 | CCKAR (0.48) | KMT2APTGES2 | |
| SCHEMBL7213023 | 0.76 | SLC10A6 (0.73) | SLC10A2SLC10A1SLC10A6ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458845-B1 | METHOD OF ANTAGONIZING A MACROPHAGE SCAVENGER RECEPTOR COMPRISING ADMINISTERING TO A SUBJECT IN NEED OF TREATMENT AN EFFECTIVE AMOUNT OF AN N-PHENYL-2-(3-TRIFLUOROMETHYLPHENYLSULFONAMIDO)BENZAMIDE, A | SMITHKLINE BEECHAM CORPORATION | 2002-10-01 | — | — | US | claimed |