Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2525070 | 0.87 | CA12 (0.33) | NPC1MAPTRAB9ASMN1; SMN2ENPP3 | |
| SCHEMBL5364589 | 0.83 | PDCD1 (0.30) | — | |
| SCHEMBL28266415 | 0.82 | ALDH1A1 (0.34) | NPC1MAPTRAB9ASMN1; SMN2ENPP3 | |
| SCHEMBL21980377 | 0.82 | CA12 (0.31) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8573143 | 0.82 | KDM1A (0.31) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL7629064 | 0.81 | GSTP1 (0.34) | DHFR | |
| SCHEMBL7640575 | 0.81 | CA12 (0.33) | NPC1MAPTRAB9ASMN1; SMN2ENPP3 | |
| SCHEMBL7639241 | 0.81 | CA12 (0.33) | NPC1MAPTRAB9ASMN1; SMN2ENPP3 | |
| SCHEMBL2524671 | 0.81 | NPC1 (0.30) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL4927713 | 0.80 | KDM4E (0.30) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417302-B1 | REACTION PRODUCT OF DI(PENTAFLUOROPHENYL) BORINIC ACID AND ORGANOALUMINUM COMPOUND; OLEFIN POLYMERIZATION COORDINATION CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2002-07-09 | — | — | US | disclosed |