Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | DRD1 | P21728 | 13/20 | 0.65 |
| ▸ | DRD2 | P14416 | 8/20 | 0.65 |
| ▸ | DRD5 | P21918 | 3/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.59 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.59 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.59 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.59 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.59 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.59 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.59 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.59 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10345386 | 0.99 | DRD1 (0.66) | HTR2CHTR2AHTR2BDRD1DRD2 | |
| SCHEMBL10746447 | 0.87 | HTR2C (0.63) | HTR2CHTR2AHTR2BDRD1DRD2 | |
| SCHEMBL10745233 | 0.86 | HTR2C (0.59) | HTR2CHTR2AHTR2BDRD1DRD2 | |
| SCHEMBL10345842 | 0.84 | HTR2C (0.56) | HTR2CHTR2AHTR2BDRD1DRD2 | |
| SCHEMBL10746722 | 0.82 | HTR2C (0.54) | HTR2CHTR2AHTR2BDRD1DRD2 | |
| SCHEMBL7320752 | 0.82 | DRD1 (0.81) | DRD1DRD2DRD5TAAR1KDM4E | |
| SCHEMBL7620194 | 0.82 | DRD1 (0.81) | DRD1DRD2DRD5TAAR1KDM4E | |
| SCHEMBL7621209 | 0.82 | DRD1 (0.81) | DRD1DRD2DRD5TAAR1KDM4E | |
| SCHEMBL10345843 | 0.81 | HTR2C (0.59) | HTR2CHTR2AHTR2BDRD1DRD2 | |
| Fumaric Acid SCHEMBL10345846 | 0.81 | DRD1 (0.57) | HTR2CHTR2AHTR2BDRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005300-A1 | Substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, process for the preparation thereof, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-11-14 | — | — | EP | claimed |
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | CHACONNE NSI CO., LTD. (KR) | 2002-02-14 | — | — | US | disclosed |
| US-4707483-A | 1-phenyl-3-benzazepines and their use for treating gastrointestinal motility disorders | SMITHKLINE BECKMAN CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0244088-A2 | 1-Phenyl-3-benzazepine compounds and medicaments containing these compounds for treating gastrointestinal motility disorders | SMITHKLINE BEECHAM CORPORATION (US) | 1987-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019389-A1 | Urea derivative useful as an anti-cancer agent and process for preparing same | UTS2R, SLC14A1, URB2 | HTR2C 4541/4885HTR2A 4342/4885HTR2B 3194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.