Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP9 | P55211 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30267832 | 1.00 | TSHR (0.53) | TSHRNPSR1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL19953614 | 0.85 | SMN1; SMN2 (0.49) | TSHRNPSR1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9597965 | 0.79 | TSHR (0.49) | TSHRNPSR1SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL10331843 | 0.78 | TSHR (0.48) | TSHRNPSR1ALDH1A1GAAMAPT | |
| SCHEMBL30267812 | 0.76 | TSHR (0.42) | TSHRNPSR1ALDH1A1GAAMAPT | |
| SCHEMBL17528631 | 0.75 | TSHR (0.46) | TSHRNPSR1ALDH1A1GAAMAPT | |
| SCHEMBL31350550 | 0.75 | SMN1; SMN2 (0.76) | SMN1; SMN2GAAMAPTANPEPAHR | |
| SCHEMBL11439131 | 0.75 | SMN1; SMN2 (0.76) | SMN1; SMN2GAAMAPTANPEPAHR | |
| SCHEMBL21035184 | 0.75 | SMN1; SMN2 (0.76) | SMN1; SMN2GAAMAPTANPEPAHR | |
| SCHEMBL21035183 | 0.75 | SMN1; SMN2 (0.76) | SMN1; SMN2GAAMAPTANPEPAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020142998-A1 | Bile-acid conjugates for providing sustained systemic concentrations of drugs | XENOPORT INC. | 2002-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020142998-A1 | Bile-acid conjugates for providing sustained systemic concentrations of drugs | SLC10A1, SLC10A2, ABCB11 | TSHR 2831/4885NPSR1 663/4885SMN1; SMN2 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.