Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626184 | 0.90 | NPC1 (0.49) | NPC1RAB9AMAPTNPSR1CTSD | |
| SCHEMBL7632324 | 0.88 | KMT2A (0.51) | NPC1RAB9AALDH1A1KMT2AHTT | |
| SCHEMBL7632033 | 0.87 | NPC1 (0.50) | NPC1RAB9AMAPTNPSR1CTSD | |
| SCHEMBL2612520 | 0.86 | ALDH1A1 (0.54) | NPC1RAB9AMAPTNPSR1CTSD | |
| SCHEMBL7628244 | 0.86 | HCRTR1 (0.47) | MAPTNPSR1ALDH1A1KMT2AHTT | |
| SCHEMBL7630853 | 0.84 | CA12 (0.45) | NPSR1ALDH1A1KMT2AL3MBTL1GAA | |
| SCHEMBL7624304 | 0.84 | NPC1 (0.47) | NPC1RAB9AMAPTNPSR1CTSD | |
| SCHEMBL7625512 | 0.82 | ADRB2 (0.46) | NPC1RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL7627642 | 0.82 | KMT2A (0.52) | NPC1RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL7629075 | 0.82 | MEN1 (0.49) | RAB9AMAPTNPSR1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |