SCHEMBL7630716

SCHEMBL7630716

[CH2]C(C)[C](OOC(=O)c1ccc([Si](C=C)(C=C)CC)cc1)OOC(=O)c1ccc([Si](C=C)(C=C)CC)cc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.33
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
MAPT P10636 1/20 0.31
F2 P00734 1/20 0.31
LMNA P02545 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7625121 0.87 ALDH1A1 (0.32) CYP4F2CYP4A11MAPTF2LMNA
SCHEMBL7630931 0.84 STAT3 (0.33) STAT3MAPT
SCHEMBL7635518 0.83 LMNA (0.34) STAT3F2LMNATHRB
SCHEMBL7626099 0.83 LMNA (0.34) STAT3F2LMNATHRB
SCHEMBL7629140 0.82 NR1H2 (0.38) CYP4F2CYP4A11F2LMNA
SCHEMBL7628476 0.82 ESR1 (0.35) F2LMNATHRB
SCHEMBL7626363 0.81 LMNA (0.33) F2LMNA
SCHEMBL7632193 0.81 HPGD (0.33) STAT3MAPTF2LMNATHRB
SCHEMBL7628794 0.80 MAPT (0.32) STAT3MAPT
SCHEMBL7625498 0.80 ESR1 (0.32) F2LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed