SCHEMBL7631036

SCHEMBL7631036

O=Cc1cc(Cl)c(Cl)c(Cl)c1Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.47
▸ LMNA P02545 3/20 0.47
▸ GAA P10253 1/20 0.47
▸ RHEB Q15382 3/20 0.40
▸ TDP1 Q9NUW8 3/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ MAPT P10636 2/20 0.38
▸ POLB P06746 1/20 0.38
▸ ORAI1 Q96D31 1/20 0.37
▸ ERN1 O75460 1/20 0.37
▸ TTR P02766 1/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ CYP1A2 P05177 2/20 0.36
▸ CYP2C9 P11712 2/20 0.36
▸ CYP2C19 P33261 2/20 0.36
▸ LTA4H P09960 1/20 0.35
▸ TSHR P16473 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ STK39 Q9UEW8 1/20 0.35
▸ THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10770981 0.81 KMT2A (0.49) KMT2ALMNAGAARHEBTDP1
SCHEMBL14920693 0.78 KMT2A (0.49) KMT2ALMNAGAARHEBTDP1
SCHEMBL21129969 0.76 LMNA (0.59) KMT2ALMNAGAATDP1ERN1
SCHEMBL11298539 0.76 KMT2A (0.55) KMT2ALMNAGAARHEBTDP1
SCHEMBL10425326 0.75 CYP1A2 (0.44) KMT2ARHEBTDP1MEN1MAPT
SCHEMBL1767624 0.75 RHEB (0.47) KMT2ARHEBTDP1MEN1MAPT
SCHEMBL24189619 0.72 LMNA (0.50) KMT2ALMNAGAAERN1ALDH1A1
SCHEMBL7762056 0.72 LMNA (0.50) KMT2ALMNAGAATDP1MAPT
SCHEMBL30397192 0.72 LMNA (0.50) KMT2ALMNAGAAERN1ALDH1A1
SCHEMBL14920058 0.72 KMT2A (0.46) KMT2ALMNAGAARHEBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6495040-B1 Septic tank filtering system ZOELLER CO. 2002-12-17 — — US disclosed
US-6331247-B1 Septic tank filtering system ZOELLER COMPANY 2001-12-18 — — US disclosed
WO-2000076618-A1 SEPTIC TANK FILTERING SYSTEM ZOELLER COMPANY (US) 2000-12-21 — — WO disclosed
US-6136190-A Septic tank filtering system ZOELLER CO. (US) 2000-10-24 — — US disclosed
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