Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24189619 | 1.00 | LMNA (0.50) | LMNAGAAKMT2AKMOERN1 | |
| SCHEMBL7762056 | 0.86 | LMNA (0.50) | LMNAGAAKMT2AKMOERN1 | |
| SCHEMBL24104988 | 0.82 | ALDH1A1 (0.48) | GAAKMT2AKMOPGRLTA4H | |
| SCHEMBL11490625 | 0.79 | LMNA (0.50) | LMNAGAAKMT2AERN1PGR | |
| SCHEMBL6093640 | 0.79 | ERN1 (0.61) | LMNAGAAKMT2AERN1LTA4H | |
| SCHEMBL28250579 | 0.79 | KMT2A (0.50) | LMNAGAAKMT2AERN1LTA4H | |
| SCHEMBL31556425 | 0.79 | LMNA (0.50) | LMNAGAAKMT2AERN1LTA4H | |
| SCHEMBL2536648 | 0.79 | LMNA (0.50) | LMNAGAAKMT2AERN1LTA4H | |
| SCHEMBL16397775 | 0.77 | GSTP1 (0.53) | LMNAGAAKMT2AERN1LTA4H | |
| SCHEMBL30402795 | 0.77 | MAOA (0.56) | KMT2AGSTP1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |