SCHEMBL7631073

SCHEMBL7631073

C=C(C)C(=O)c1ccc(C(C)(C)c2ccc(C(=O)C(=C)C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
CES2 O00748 3/20 0.43
CES1 P23141 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ESR1 P03372 3/20 0.43
ESR2 Q92731 3/20 0.43
CYP3A4 P08684 2/20 0.43
HPGD P15428 2/20 0.43
AR P10275 1/20 0.43
TSHR P16473 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
HTR6 P50406 1/20 0.43
ESRRG P62508 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HSD17B10 Q99714 1/20 0.43
HDAC1 Q13547 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14400014 0.88 MAPT (0.55) MAPTTHRATHRBCES2CES1
SCHEMBL28670034 0.84 MAPT (0.71) MAPTTHRATHRBCES2CES1
SCHEMBL9780335 0.82 CES2 (0.69) MAPTTHRATHRBCES2CES1
SCHEMBL25547743 0.81 MAPT (0.49) MAPTTHRATHRBCES2CES1
SCHEMBL13228130 0.81 THRA (0.49) MAPTTHRATHRBCES2CES1
SCHEMBL9472225 0.78 HPGD (0.50) MAPTMEN1KMT2AESR1ESR2
SCHEMBL5852775 0.76 MAPT (0.61) MAPTTHRATHRBCES2CES1
SCHEMBL6272776 0.76 MAPT (0.61) MAPTTHRATHRBCES2CES1
SCHEMBL2401025 0.76 MAPT (0.61) MAPTTHRATHRBCES2CES1
SCHEMBL2816739 0.76 CES2 (0.68) MAPTTHRATHRBCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098696-A Methacrylate monomers for polymers with tert-amine promoters and di or trimethacrylate monomers and peroxide catalysts REM SYSTEMS, INC. (US) 1992-03-24 US claimed
US-4871534-A METHACRYLATE BINDER, METHACRYLATE POLYMER, PEROXIDE INITIATOR REM SYSTEMS, INC. (US) 1989-10-03 US claimed
US-4490115-A Dental material comprising adducts of 3-methacroyl-2-hydroxypropyl esters with diisocyanates SCIENTIFIC PHARMACEUTICAL, INC. (US) 1984-12-25 US claimed
US-4406625-A Adducts of 1,4-bis[(3-Methacroyl-2-hydroxypropoxy)methyl]cyclohexane and derivatives thereof with isocyanates SCIENTIFIC PHARMACEUTICALS, INC. (US) 1983-09-27 US claimed
US-4380432-A METHACRYLATE, CONJUGATED DIENE ELASTOMER SCIENTIFIC PHARMACEUTICALS (US) 1983-04-19 US claimed
US-4379695-A SEALERS; BINDERS; ADHESIVES; CEMENTS; HIGH STRENGTH; CURING; IN SITU ADDITION POLYMERIZATION SCIENTIFIC PHARMACEUTICALS, INC. (US) 1983-04-12 US claimed
US-4304893-A CURABLE DENTAL MATERIALS SCIENTIFIC PHARMACEUTICALS, INC. (US) 1981-12-08 US claimed
WO-2015132734-A1 3D PRINTED NAILS MOYAL DANIEL (IL) 2015-09-11 WO disclosed
US-6455033-B1 ANTIMICROBIAL COMPOSITION; POLYMERIZABLE ACRYLIC MONOMERS; POLYMERIZATION CATALYSTS; MYCONE DENTAL CORP. 2002-09-24 US disclosed
US-5098696-A Methacrylate monomers for polymers with tert-amine promoters and di or trimethacrylate monomers and peroxide catalysts REM SYSTEMS, INC. (US) 1992-03-24 US disclosed
US-4871534-A METHACRYLATE BINDER, METHACRYLATE POLYMER, PEROXIDE INITIATOR REM SYSTEMS, INC. (US) 1989-10-03 US disclosed
US-4490115-A Dental material comprising adducts of 3-methacroyl-2-hydroxypropyl esters with diisocyanates SCIENTIFIC PHARMACEUTICAL, INC. (US) 1984-12-25 US disclosed
US-4406625-A Adducts of 1,4-bis[(3-Methacroyl-2-hydroxypropoxy)methyl]cyclohexane and derivatives thereof with isocyanates SCIENTIFIC PHARMACEUTICALS, INC. (US) 1983-09-27 US disclosed
US-4379695-A SEALERS; BINDERS; ADHESIVES; CEMENTS; HIGH STRENGTH; CURING; IN SITU ADDITION POLYMERIZATION SCIENTIFIC PHARMACEUTICALS, INC. (US) 1983-04-12 US disclosed
US-4373086-A Curable resin composition from cyanate ester and acrylic ester MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-02-08 US disclosed
US-4362888-A CEMENTS SCIENTIFIC PHARMACEUTICALS, INC. (US) 1982-12-07 US disclosed
US-4360693-A CURABLE DENTAL MATERIAL SCIENTIFIC PHARMACEUTICALS, INC. (US) 1982-11-23 US disclosed
US-4337349-A ACRYLIC RESIN MONOMERS; DENTISTRY; DENTURES; WEAR RESISTANCE SCIENTIFIC PHARMACEUTICALS, INC. (US) 1982-06-29 US disclosed
US-4304893-A CURABLE DENTAL MATERIALS SCIENTIFIC PHARMACEUTICALS, INC. (US) 1981-12-08 US disclosed
US-4229431-A IN SITU POLYMERIZATION LEE PHARMACEUTICALS (US) 1980-10-21 US disclosed