Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PLK1 | P53350 | 2/20 | 0.66 |
| ▸ | THRB | P10828 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.57 |
| ▸ | THRA | P10827 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634965 | 0.92 | L3MBTL1 (0.64) | L3MBTL1PLK1THRBPOLBCTDSP1 | |
| SCHEMBL14098923 | 0.92 | KMT2A (0.61) | L3MBTL1PLK1THRBPOLBCTDSP1 | |
| SCHEMBL2362399 | 0.89 | CYP4A11 (0.60) | L3MBTL1PLK1THRBPOLBCTDSP1 | |
| SCHEMBL7633932 | 0.88 | PLK1 (0.68) | PLK1THRBALDH1A1HAO1THRA | |
| SCHEMBL15580575 | 0.88 | NPC1 (0.59) | L3MBTL1PLK1ALDH1A1KMT2ANPC1 | |
| SCHEMBL10021819 | 0.87 | L3MBTL1 (0.67) | L3MBTL1PLK1THRBPOLBCTDSP1 | |
| SCHEMBL30089521 | 0.87 | L3MBTL1 (0.85) | L3MBTL1PLK1THRBPOLBCTDSP1 | |
| SCHEMBL21126912 | 0.87 | L3MBTL1 (0.57) | L3MBTL1PLK1THRBPOLBCTDSP1 | |
| SCHEMBL7630228 | 0.86 | NPC1 (0.58) | L3MBTL1PLK1THRBALDH1A1NPC1 | |
| SCHEMBL11135316 | 0.85 | L3MBTL1 (0.56) | L3MBTL1PLK1THRBPOLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448304-B1 | POLYURETHANE, POLYTHIOURETHANE OR DIETHYLENE GLYCOL BISALLYLCARBONATE POLYMER; DIPPING IN SOLUTION CONTAINING A DIBENZOYLMETHANE OR A BENZOTRIZOLE COMPOUND; PLASTIC LENS FOR SPECTACLES WHICH ABSORBS ULTRAVIOLET RAYS; LOW YELLOWNESS | HOYA CORPORATION (JP) | 2002-09-10 | — | — | US | disclosed |