Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.68 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.68 |
| ▸ | THRA | P10827 | 7/20 | 0.64 |
| ▸ | THRB | P10828 | 7/20 | 0.64 |
| ▸ | RARB | P10826 | 5/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7638853 | 0.93 | TRPV1 (0.65) | PLK1HAO1THRATHRBRARB | |
| SCHEMBL12620502 | 0.93 | HAO1 (0.60) | PLK1HAO1THRATHRBRARB | |
| SCHEMBL1577439 | 0.92 | HAO1 (0.79) | HAO1THRATHRBRARBALDH1A1 | |
| SCHEMBL28937871 | 0.91 | HAO1 (0.62) | PLK1HAO1THRATHRBRARB | |
| SCHEMBL2354104 | 0.90 | CYP4A11 (0.66) | PLK1HAO1THRATHRBRARB | |
| SCHEMBL7637309 | 0.88 | MMP1 (0.58) | PLK1HAO1THRATHRBALDH1A1 | |
| SCHEMBL3375914 | 0.88 | ALDH1A1 (0.56) | PLK1HAO1THRATHRBALDH1A1 | |
| SCHEMBL30089476 | 0.88 | THRA (0.70) | PLK1HAO1THRATHRBRARB | |
| SCHEMBL10031544 | 0.88 | THRA (0.64) | PLK1HAO1THRATHRBRARB | |
| SCHEMBL7631396 | 0.88 | L3MBTL1 (0.67) | PLK1HAO1THRATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116869-A | POLYMERIZATION | PHILLIPS PETROLEUM COMPANY (US) | 1978-09-26 | — | — | US | claimed |
| US-4095017-A | VINYL MONOMER POLYMERIZATION OR COPOLYMERIZATION CATALYZED BY ORGANOALUMINUM-ORGANOPHOSPHINE-METAL SALT OF A BETA-DIKETONE CATALYST SYSTEM | PHILLIPS PETROLEUM COMPANY (US) | 1978-06-13 | — | — | US | claimed |
| US-4020018-A | Alkene oxide or acrylate polymerization or copolymerization catalyzed by organoaluminum-organophosphine-metal salt of a beta-diketone | PHILLIPS PETROLEUM COMPANY (US) | 1977-04-26 | — | — | US | claimed |
| US-6448304-B1 | POLYURETHANE, POLYTHIOURETHANE OR DIETHYLENE GLYCOL BISALLYLCARBONATE POLYMER; DIPPING IN SOLUTION CONTAINING A DIBENZOYLMETHANE OR A BENZOTRIZOLE COMPOUND; PLASTIC LENS FOR SPECTACLES WHICH ABSORBS ULTRAVIOLET RAYS; LOW YELLOWNESS | HOYA CORPORATION (JP) | 2002-09-10 | — | — | US | disclosed |
| US-4116869-A | POLYMERIZATION | PHILLIPS PETROLEUM COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4095017-A | VINYL MONOMER POLYMERIZATION OR COPOLYMERIZATION CATALYZED BY ORGANOALUMINUM-ORGANOPHOSPHINE-METAL SALT OF A BETA-DIKETONE CATALYST SYSTEM | PHILLIPS PETROLEUM COMPANY (US) | 1978-06-13 | — | — | US | disclosed |
| US-4020018-A | Alkene oxide or acrylate polymerization or copolymerization catalyzed by organoaluminum-organophosphine-metal salt of a beta-diketone | PHILLIPS PETROLEUM COMPANY (US) | 1977-04-26 | — | — | US | disclosed |