SCHEMBL763142

SCHEMBL763142

C=C(C(=O)O)c1ccc(C#Cc2ccc(CCCC)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.53
THRA P10827 6/20 0.51
THRB P10828 6/20 0.51
PLK1 P53350 1/20 0.49
ALDH1A1 P00352 2/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
FFAR1 O14842 2/20 0.48
FFAR4 Q5NUL3 1/20 0.47
TRPV1 Q8NER1 1/20 0.47
HAO1 Q9UJM8 1/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
RARA P10276 1/20 0.47
MAPT P10636 1/20 0.47
MTOR P42345 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13578977 0.96 THRA (0.55) RARBTHRATHRBALDH1A1FFAR1
SCHEMBL762946 0.92 ACACB (0.50) THRBPLK1ALDH1A1FFAR1FFAR4
SCHEMBL28645496 0.91 RARB (0.62) RARBTHRATHRBPLK1ALDH1A1
SCHEMBL2356098 0.84 THRA (0.67) RARBTHRATHRBALDH1A1HAO1
SCHEMBL5547984 0.84 THRA (0.67) RARBTHRATHRBALDH1A1HAO1
SCHEMBL10651489 0.84 THRA (0.67) RARBTHRATHRBALDH1A1HAO1
SCHEMBL2722720 0.84 THRA (0.67) RARBTHRATHRBALDH1A1HAO1
SCHEMBL1811178 0.84 RARB (0.73) RARBTHRATHRBPLK1ALDH1A1
SCHEMBL2402922 0.83 RARB (0.71) RARBTHRATHRBPLK1ALDH1A1
SCHEMBL9418034 0.81 HSD17B10 (0.56) RARBTHRATHRBPLK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8139189-B2 Liquid crystal display having particular oblique vapor deposition-alignment layer with ferroelectric liquid crystal DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-20 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed
US-8130358-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-06 US disclosed
US-8009266-B2 Process for producing liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2011-08-30 US disclosed
US-7871540-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2011-01-18 US disclosed
US-20100060844-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-11 US disclosed
US-20100053525-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-04 US disclosed
US-20100007832-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-01-14 US disclosed
EP-2093610-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL DISPLAY ELEMENT Dai Nippon Printing Co., Ltd. (JP) 2009-08-26 EP disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 US disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 RARB 3123/4885THRA 2549/4885THRB 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.