SCHEMBL762946

SCHEMBL762946

C=C(C(=O)O)c1ccc(C#Cc2ccc(CCC)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACACB O00763 3/20 0.50
THRB P10828 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
FFAR1 O14842 9/20 0.48
PLK1 P53350 1/20 0.47
FFAR4 Q5NUL3 2/20 0.46
POLB P06746 2/20 0.43
CTDSP1 Q9GZU7 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL763142 0.92 RARB (0.53) THRBFFAR1PLK1FFAR4ALDH1A1
SCHEMBL13578977 0.91 THRA (0.55) THRBFFAR1FFAR4ALDH1A1
SCHEMBL8620456 0.85 RARB (0.57) THRBL3MBTL1PLK1POLBCTDSP1
SCHEMBL762846 0.82 RARB (0.50) ACACBFFAR1FFAR4
SCHEMBL28645496 0.81 RARB (0.62) THRBPLK1ALDH1A1
SCHEMBL14029964 0.81 THRB (0.54) THRBL3MBTL1PLK1POLBCTDSP1
SCHEMBL14192330 0.79 THRB (0.81) ACACBTHRBL3MBTL1PLK1ALDH1A1
SCHEMBL10651489 0.79 THRA (0.67) THRBALDH1A1
SCHEMBL2356098 0.79 THRA (0.67) THRBALDH1A1
SCHEMBL2722720 0.79 THRA (0.67) THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8139189-B2 Liquid crystal display having particular oblique vapor deposition-alignment layer with ferroelectric liquid crystal DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-20 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed
US-8130358-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-06 US disclosed
US-8094269-B2 Liquid crystal display device, manufacturing method thereof, and color filter substrate HITACHI DISPLAYS, LTD. (JP) 2012-01-10 US disclosed
US-8009266-B2 Process for producing liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2011-08-30 US disclosed
US-7871540-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2011-01-18 US disclosed
US-7812905-B2 Liquid crystal display device and manufacturing method thereof HITACHI DISPLAYS, LTD. (JP) 2010-10-12 US disclosed
US-20100060844-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-11 US disclosed
US-20100053525-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-04 US disclosed
US-20100007832-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-01-14 US disclosed
EP-2093610-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL DISPLAY ELEMENT Dai Nippon Printing Co., Ltd. (JP) 2009-08-26 EP disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 US disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 US disclosed
US-20090021675-A1 Liquid Crystal Display Device, Manufacturing Method Thereof, and Color Filter Substrate IPS ALPHA SUPPORT CO., LTD. (JP) 2009-01-22 US disclosed
US-20080074588-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF MAGNOLIA PURPLE CORPORATION (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 ACACB 4059/4885THRB 3657/4885L3MBTL1 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.