Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10930487 | 0.82 | MAPT (0.31) | MAPT | |
| SCHEMBL334817 | 0.81 | MMP8 (0.32) | MAPTMMP8 | |
| SCHEMBL4293915 | 0.80 | — | — | |
| SCHEMBL9306468 | 0.80 | ALDH1A1 (0.32) | MAPT | |
| SCHEMBL9550958 | 0.79 | MAPT (0.33) | MAPT | |
| SCHEMBL3371032 | 0.79 | MAPT (0.35) | MAPTMMP8 | |
| SCHEMBL335585 | 0.78 | MEN1 (0.30) | — | |
| SCHEMBL18489636 | 0.77 | MAPT (0.34) | MAPT | |
| SCHEMBL4302210 | 0.76 | — | — | |
| SCHEMBL10836351 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417391-B2 | HYDROGENATION AND REACTION WITH FORMALDEHYDE IN PRESENCE OF SOLVENT AND MIXTURE OF HYDROGENATION CATALYST AND KNOEVENAGEL CATALYST, ISOLATION, THEN THERMOLYSIS | DEGUSSA AG (DE) | 2002-07-09 | — | — | US | disclosed |
| US-20010044554-A1 | PROCESS FOR THE PREPARATION OF 2-METHYL-1,3-DICARBOXYLATES | DEGUSSA AG (DE) | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044554-A1 | PROCESS FOR THE PREPARATION OF 2-METHYL-1,3-DICARBOXYLATES | MCCC2, HADHB, CARM1 | MAPT 2428/4885MMP8 3411/4885PRKCA 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.