SCHEMBL7632344

SCHEMBL7632344

CC=[Hf](C)(C)(C1C(C)=Cc2ccccc21)C1C(C)=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218503 0.82 LMNA (0.33) LMNAALDH1A1SMN1; SMN2TDP1
SCHEMBL7642594 0.81 LMNA (0.32) LMNAALDH1A1SMN1; SMN2TDP1
SCHEMBL7634767 0.78 LMNA (0.33) LMNAALDH1A1SMN1; SMN2TDP1
SCHEMBL7645858 0.78 LMNA (0.31) LMNAALDH1A1SMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL7933190 0.76 LMNA (0.31) LMNAALDH1A1SMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL818447 0.76 LMNA (0.31) LMNAALDH1A1SMN1; SMN2TDP1
Hydrochloric Acid SCHEMBL7935728 0.76 LMNA (0.31) LMNA
SCHEMBL7627638 0.76 LMNA (0.32) LMNAALDH1A1SMN1; SMN2TDP1
SCHEMBL1049999 0.75 LMNA (0.30) LMNA
Hydrochloric Acid SCHEMBL5854698 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849288-B1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORP (JP) 2002-11-27 EP disclosed
US-5906955-A Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1999-05-25 US disclosed
EP-0849288-A1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1998-06-24 EP disclosed