Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519858 | 0.81 | LMNA (0.57) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL7160143 | 0.81 | PIK3CD (0.37) | PIK3CD | |
| SCHEMBL13590014 | 0.79 | LMNA (0.62) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL10041494 | 0.79 | LMNA (0.62) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL6938845 | 0.79 | LMNA (0.62) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL14047287 | 0.79 | LMNA (0.62) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL22015868 | 0.79 | LMNA (0.62) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL11601594 | 0.78 | LMNA (0.87) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL1269883 | 0.77 | LMNA (0.57) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL16174558 | 0.76 | LMNA (0.64) | LMNABLMPTPN1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790260-B1 | Solid catalyst components for polymerization | JAPAN POLYOLEFINS CO LTD (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5902765-A | MADE BY REACTING A MAGNESIUM DIHALIDE WITH TETRAHYDROFURAN, BUTYL ETHER OR DIETHYL ETHER AND TREATING THE SOLID SUBSTANCE WITH AN ELECTRON DONATIVE COMPOUND HAVING TWO OR MORE ALKOXY OR ESTER GROUPS, CONTACTING WITH TITANIUM; STEREOREGULARITY | JAPAN POLYOLEFINS CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0790260-A1 | Solid catalyst components for polymerization | JAPAN POLYOLEFINS CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |