SCHEMBL8519858

SCHEMBL8519858

COCC(C)CCCC(C)C

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
BLM P54132 1/20 0.41
PTPN1 P18031 2/20 0.36
MEN1 O00255 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
PIK3CD O00329 1/20 0.34
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1269883 0.95 LMNA (0.57) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL28234726 0.92 LMNA (0.43) LMNABLM
SCHEMBL28061656 0.83 PIK3CD (0.37) LMNAPIK3CDALDH1A1
SCHEMBL13590014 0.82 LMNA (0.62) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL22015868 0.82 LMNA (0.62) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL10041494 0.82 LMNA (0.62) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL14047287 0.82 LMNA (0.62) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL10667063 0.82 LMNA (0.36) LMNA
SCHEMBL6938845 0.82 LMNA (0.62) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL7632971 0.81 LMNA (0.54) LMNABLMPTPN1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105837714-B The manufacturing method of solid catalyst component for olefin polymerization, the manufacturing method of polymerization of olefines catalyst and olefin polymer 东邦钛株式会社 2018-07-20 CN disclosed
CN-104470953-B Process for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and process for producing olefin polymer 东邦钛株式会社 2017-11-14 CN disclosed
CN-104640887-B The manufacture method of manufacture method for the ingredient of solid catalyst of olefin polymerization, the catalyst for olefin polymerization and olefin polymerization 东邦钛株式会社 2017-08-29 CN disclosed
CN-104039841-B Catalyst component 博里利斯股份公司 2017-02-22 CN disclosed
CN-104640885-B Polymerization of olefines ingredient of solid catalyst, polymerization of olefines catalyst and the manufacture method of olefin polymer 东邦钛株式会社 2016-11-16 CN disclosed
CN-105837714-A METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR USE IN POLYMERIZATION OF OLEFIN, CATALYST FOR USE IN POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING OLEFIN POLYMER 东邦钛株式会社 2016-08-10 CN disclosed
WO-2014011695-A2 PRODRUGS OF PEPTIDE EPOXY KETONE PROTEASE INHIBITORS ONYX THERAPEUTICS, INC. (US) 2014-01-16 WO disclosed
US-5880146-A INTERLEUKINS AND IMMUNOLOGY FOR AUTOIMMUNE DISEASES FUJI IMMUNOPHARMACEUTICALS CORPORATION (US) 1999-03-09 US disclosed