Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Anthranilic Acid SCHEMBL3269369 | 0.96 | MMP2 (0.57) | MMP2MAPTGAAALDH1A1ALOX15 | |
| Anthranilic Acid SCHEMBL9861296 | 0.96 | MMP2 (0.61) | MMP2MAPTGAAALDH1A1ALOX15 | |
| Anthranilic Acid SCHEMBL29802554 | 0.91 | ALDH1A1 (0.65) | MMP2MAPTGAAALDH1A1ALOX15 | |
| Anthranilic Acid SCHEMBL362171 | 0.91 | ALDH1A1 (0.65) | MMP2MAPTGAAALDH1A1ALOX15 | |
| Anthranilic Acid SCHEMBL29365173 | 0.91 | ALDH1A1 (0.65) | MMP2MAPTGAAALDH1A1ALOX15 | |
| Anthranilic Acid SCHEMBL3110791 | 0.91 | ALDH1A1 (0.65) | MMP2MAPTGAAALDH1A1ALOX15 | |
| Anthranilic Acid SCHEMBL2961107 | 0.91 | ALDH1A1 (0.65) | MMP2MAPTGAAALDH1A1ALOX15 | |
| Anthranilic Acid SCHEMBL2953168 | 0.91 | ALDH1A1 (0.65) | MMP2MAPTGAAALDH1A1ALOX15 | |
| Anthranilic Acid SCHEMBL675 | 0.91 | ALDH1A1 (0.65) | MMP2MAPTGAAALDH1A1ALOX15 | |
| Anthranilic Acid SCHEMBL9861966 | 0.90 | MMP2 (0.60) | MMP2MAPTGAAALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101687886-B | Seven-membered ring compound and pharmaceutical application thereof in preventing and treating diabetes and metabolic syndrome | SHANGHAI INST MATERIA MEDICA | 2012-11-07 | — | — | CN | disclosed |
| US-6369098-B1 | PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-.GAMMA. (PPAR.GAMMA.) AND/OR PPAR.ALPHA TREATMENT OF ENDOCRINE, SKIN, CARDIOVASCULAR, IMMUNOLOGICAL, NEUROLOGICAL, NEUROPSYCHIATRIC, NEOPLASTIC AND CHRONIC VIRAL DISEASES OF VARIOUS ORGANS | BETHESDA PHARMACEUTICALS, INC. | 2002-04-09 | — | — | US | disclosed |
| WO-2001025226-A1 | DITHIOLANE DERIVATIVES | BETHESDA PHARMACEUTICALS, INC. (US) | 2001-04-12 | — | — | WO | disclosed |