Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633253 | 1.00 | LDHA (0.34) | LDHALDHBADRB1OPRM1OPRD1 | |
| SCHEMBL8009542 | 0.92 | DRD2 (0.33) | — | |
| SCHEMBL7642626 | 0.90 | LDHA (0.31) | LDHA | |
| SCHEMBL7635120 | 0.88 | LDHA (0.31) | LDHALDHB | |
| SCHEMBL7633268 | 0.88 | LDHA (0.31) | LDHALDHB | |
| SCHEMBL6296292 | 0.87 | LDHA (0.30) | LDHALDHB | |
| SCHEMBL6297602 | 0.85 | — | — | |
| SCHEMBL6296398 | 0.85 | LDHA (0.33) | LDHALDHB | |
| SCHEMBL6296396 | 0.85 | LDHA (0.33) | LDHALDHB | |
| SCHEMBL6303245 | 0.85 | LDHA (0.33) | LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | claimed |
| US-6380400-B1 | DIMETHYLTHIOCARBAMIC ACID ESTER; VIRICIDES | FEDIJ VICTOR (US) | 2002-04-30 | — | — | US | disclosed |
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |