SCHEMBL7633679

SCHEMBL7633679

[CH2]COCCOC[C](OOC(=O)c1ccccc1C)OOC(=O)c1ccccc1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
NPC1 O15118 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
RAB9A P51151 1/20 0.37
ADRB2 P07550 2/20 0.36
ADRB1 P08588 2/20 0.36
ADRB3 P13945 2/20 0.36
TSHR P16473 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ERCC5 P28715 1/20 0.35
FEN1 P39748 1/20 0.35
BCHE P06276 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633979 0.93 MEN1 (0.43) MEN1KMT2ANPC1TDP1SMN1; SMN2
SCHEMBL7634280 0.84 NPC1 (0.42) KMT2ANPC1SMN1; SMN2LMNAALDH1A1
SCHEMBL7634801 0.82 KMT2A (0.44) MEN1KMT2ANPC1TDP1SMN1; SMN2
SCHEMBL7628575 0.82 ALDH1A1 (0.46) MEN1KMT2ASMN1; SMN2LMNAALDH1A1
SCHEMBL7633664 0.81 SCN1A (0.43) MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL7626123 0.81 KMT2A (0.43) MEN1KMT2ANPC1TDP1SMN1; SMN2
SCHEMBL7627403 0.80 LMNA (0.53) KMT2ANPC1TDP1SMN1; SMN2LMNA
SCHEMBL7632714 0.78 KMT2A (0.48) MEN1KMT2ANPC1TDP1SMN1; SMN2
SCHEMBL7628206 0.78 MEN1 (0.41) MEN1KMT2ANPC1TDP1SMN1; SMN2
SCHEMBL7625707 0.78 MEN1 (0.37) MEN1KMT2ANPC1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed