⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909202 | 0.81 | — | — | |
| SCHEMBL18575620 | 0.73 | MEN1 (0.33) | — | |
| SCHEMBL5963338 | 0.70 | TSHR (0.34) | — | |
| SCHEMBL15921186 | 0.69 | — | — | |
| SCHEMBL2379126 | 0.69 | LMNA (0.32) | — | |
| SCHEMBL16594818 | 0.69 | TSHR (0.31) | — | |
| SCHEMBL55574 | 0.67 | — | — | |
| SCHEMBL306389 | 0.67 | TSHR (0.40) | — | |
| SCHEMBL6078609 | 0.67 | LMNA (0.32) | — | |
| SCHEMBL4689492 | 0.65 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716506-A | Hemiasterlin derivatives for conjugation and therapy | 苏特罗生物制药公司 | 2022-07-08 | — | — | CN | disclosed |
| US-10344389-B2 | Low temperature electrolytes for solid oxide cells having high ionic conductivity | FCET, INC. (US) | 2019-07-09 | — | — | US | disclosed |
| US-20180023205-A1 | Low Temperature Electrolytes for Solid Oxide Cells Having High Ionic Conductivity | FCET, INC. (US) | 2018-01-25 | — | — | US | disclosed |
| EP-1112272-B1 | MUSCARINIC AGONISTS AND ANTAGONISTS | UCB SA (BE) | 2002-11-13 | — | — | EP | disclosed |