Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594818 | 0.87 | TSHR (0.31) | TSHR | |
| SCHEMBL9414024 | 0.86 | TSHR (0.37) | TSHR | |
| SCHEMBL9029419 | 0.86 | TSHR (0.37) | TSHRALDH1A1ALOX15 | |
| SCHEMBL28600057 | 0.82 | TSHR (0.42) | TSHRALDH1A1ALOX15 | |
| SCHEMBL2379126 | 0.82 | LMNA (0.32) | — | |
| SCHEMBL3885519 | 0.82 | TSHR (0.42) | TSHRALDH1A1ALOX15 | |
| SCHEMBL6061890 | 0.81 | ADH1B (0.36) | TSHR | |
| SCHEMBL4977381 | 0.81 | LMNA (0.39) | TSHRALDH1A1ALOX15 | |
| SCHEMBL4634958 | 0.81 | ADH1B (0.36) | TSHR | |
| SCHEMBL24224784 | 0.81 | TSHR (0.50) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113521299-B | Pyrazolopyrimidine derivative or conjugate thereof, preparation method and application thereof | 江苏恒瑞医药股份有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114126606-B | Method for dispersing a biofilm comprising gram-negative bacteria | Q生物股份有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-118213618-A | Electrolyte additive, electrolyte, lithium ion battery and electronic device | 蔚来电池科技(安徽)有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-115052596-B | ADAMTS inhibitor, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-118027131-A | Salt of steroid derivative regulator and crystal form thereof | 上海翰森生物医药科技有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117986249-A | Pyrazole derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117964682-A | Dolastatin derivative and preparation method and application thereof | 杭州爱科瑞思生物医药有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-20240132728-A1 | Bio-Based Coalescing Solvents | BATTELLE MEMORIAL INSTITUTE | 2024-04-25 | — | — | US | disclosed |
| CN-117917409-A | Crystal form of heterocyclic derivative inhibitor and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-113905743-B | CD73 inhibitors and therapeutic uses thereof | 江苏恒瑞医药股份有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-6864261-B2 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2005-03-08 | — | — | US | disclosed |
| WO-2005019353-A2 | COPOLYMER SURFACTANTS | COLUMBIA INSURANCE COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |
| US-20050039635-A1 | Copolymer surfactants | BENJAMIN MOORE & CO. | 2005-02-24 | — | — | US | disclosed |
| US-20050025741-A1 | Copolymers with (meth)acrylamides; improved separation of polynucleotides | APPLIED BIOSYSTEMS, LLC | 2005-02-03 | — | — | US | disclosed |
| WO-2004104054-A1 | POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLERA CORPORATION (US) | 2004-12-02 | — | — | WO | disclosed |
| US-20040127501-A1 | Therapeutic agents useful for treating pain | EURO-CELTIQUE S.A. (LU) | 2004-07-01 | — | — | US | disclosed |
| WO-2004029044-A1 | PYRIMIDINE COMPOUNDS AS THERAPEUTIC AGENTS | EURO-CELTIQUE, S.A. (LU) | 2004-04-08 | — | — | WO | disclosed |
| US-20040053914-A1 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. | 2004-03-18 | — | — | US | disclosed |
| WO-2003093236-A1 | 1-(PYRID-2-YL)-PIPERAZINE COMPOUNDS AS METABOTROPIC GLUTAMATE RECEPTOR INHIBITOR | EURO-CELTIQUE, S.A. (LU) | 2003-11-13 | — | — | WO | disclosed |
| EP-0086647-A2 | Pyrimidone compounds, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053914-A1 | Therapeutic agents useful for treating pain | SMN1; SMN2, OPRM1, PSEN1 | TSHR 2139/4885ALDH1A1 416/4885ALOX15 587/4885 |
| US-20040127501-A1 | Therapeutic agents useful for treating pain | CACNA1A, GRIN2A, HTT | TSHR 1813/4885ALDH1A1 516/4885ALOX15 935/4885 |
| US-20050025741-A1 | Copolymers with (meth)acrylamides; improved separation of polynucleotides | POLI, PCNA, POLL | TSHR 4259/4885ALDH1A1 3357/4885ALOX15 4522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.