SCHEMBL7633829

SCHEMBL7633829

C=C(C)C(=O)OC(F)c1ccccc1F

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
ELANE P08246 1/20 0.36
CYP3A4 P08684 1/20 0.36
GAA P10253 1/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
CNR2 P34972 1/20 0.35
MC4R P32245 3/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
HTR3A P46098 1/20 0.34
HIF1A Q16665 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL7183109 0.95 MEN1 (0.37) MEN1KMT2ACES2CES1ELANE
SCHEMBL27668701 0.83 MEN1 (0.49) MEN1KMT2ACES2CES1CYP3A4
SCHEMBL14648214 0.80 IDO1 (0.50) MEN1KMT2ACES2CES1ELANE
SCHEMBL527905 0.78 HPGD (0.44) KMT2ACES2CES1ELANECYP3A4
SCHEMBL4606754 0.75 CES2 (0.40) MEN1KMT2ACES2CES1CYP3A4
Methacrylic Acid SCHEMBL8166195 0.75 HPGD (0.42) KMT2AELANECYP3A4ALDH1A1LMNA
Hydrochloric Acid SCHEMBL3407685 0.71 GAA (0.42) MEN1KMT2ACES2CES1GAA
SCHEMBL6903312 0.70 ELANE (0.49) KMT2AELANEGAAALDH1A1LMNA
SCHEMBL27918522 0.70 MEN1 (0.50) MEN1KMT2ACES2CES1CYP3A4
SCHEMBL26862028 0.70 ESR1 (0.38) MEN1KMT2AELANECYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6388015-B1 BLEND OF NITRILE AND ALKYL ACRYLATE COPOLYMER WITH ETHYLENE-OCTENE COPOLYMER NIPPON ZEON CO., LTD. (JP) 2002-05-14 US disclosed
EP-0795580-B1 VULCANIZABLE RUBBER COMPOSITION, SEAL TO BE USED IN DYNAMIC STATE, AND MATERIAL THEREFOR NIPPON ZEON CO (JP) 2001-03-21 EP disclosed
US-6087453-A ACRYLONITRILE-BUTADIENE-UNSATURATED DICARBOXYLIC ACID DIALKYL ESTER COPOLYMER AND METAL SALT OF DIACID AND PEROXY VULCANIZATION NIPPON ZEON CO., LTD. (JP) 2000-07-11 US disclosed
EP-1008624-A1 RUBBER COMPOSITION, ELECTRIC WIRE COATING MATERIAL, AND ELECTRIC WIRE Nippon Zeon Co., Ltd. (JP) 2000-06-14 EP disclosed
US-5998531-A NITRILE RUBBER NIPPON ZEON CO LTD (JP) 1999-12-07 US disclosed
US-5852093-A Vulcanizable rubber composition, seal used in dynamic state, and sealing material NIPPON ZEON CO., LTD. (JP) 1998-12-22 US disclosed
US-5830941-A HYDROGENATED TERPOLYMER OF ACRYLONITRILE, BUTADIENE AND AN ACRYLATE OR METHACRYLATE, HYDROFLUOROCARBON RESISTANCE NIPPON ZEON CO., LTD. (JP) 1998-11-03 US disclosed
EP-0869144-A1 CURABLE RUBBER COMPOSITION FOR THE SEAL AGAINST HOT WATER NIPPON ZEON CO., LTD. (JP) 1998-10-07 EP disclosed
EP-0704480-B1 Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber NIPPON ZEON CO (JP) 1998-01-28 EP disclosed
US-5683819-A Composite of highly saturated nitrile rubber with fiber, and belt composed thereof NIPPON ZEON CO., LTD. (JP) 1997-11-04 US disclosed
EP-0704479-B1 Composite of highly saturated nitrile rubber with fiber, and belt composed thereof NIPPON ZEON CO (JP) 1997-09-24 EP disclosed
EP-0795580-A1 VULCANIZABLE RUBBER COMPOSITION, SEAL TO BE USED IN DYNAMIC STATE, AND MATERIAL THEREFOR NIPPON ZEON CO., LTD. (JP) 1997-09-17 EP disclosed
US-5651995-A Highly saturated nitrile rubber, process for producing same, vulcanizable rubber composition, aqueous emulsion and adhesive composition NIPPON ZEON CO., LTD. (JP) 1997-07-29 US disclosed
US-5556919-A Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber NIPPON ZEON CO., LTD. (JP) 1996-09-17 US disclosed
EP-0704459-A1 Highly saturated nitrile rubber, process for producing same, vulcanizable rubber composition, aqueous emulsion and adhesive composition NIPPON ZEON CO., LTD. (JP) 1996-04-03 EP disclosed
EP-0704480-A1 Rubber composition comprising nitrile group-containing highly saturated copolymer rubber and ethylenically saturated copolymer rubber NIPPON ZEON CO., LTD. (JP) 1996-04-03 EP disclosed
EP-0704479-A1 Composite of highly saturated nitrile rubber with fiber, and belt composed thereof NIPPON ZEON CO., LTD. (JP) 1996-04-03 EP disclosed
US-5013797-A Conjugated diene-acrylic ester-acrylic nitrile terpolymer; hydrogenated NIPPON ZEON CO., LTD. (JP) 1991-05-07 US disclosed
US-5013796-A Units of unsaturated nitrile, fluorine-containing vinyl monomer, conjugated diene, hydrogenated conjugated diene NIPPON ZEON CO., LTD. (JP) 1991-05-07 US disclosed
US-4956417-A UNSATURATED ESTER, CONJUGATED DIENE, HYDROGENATED CONJUGATED DIENES COPOLYMERS HAVING HEAT RESISTANCE AND OZONE RESISTANCE NIPPON ZEON CO., LTD. (JP) 1990-09-11 US disclosed