Methacrylic Acid

Methacrylic Acid

SCHEMBL7183109

C=C(C)C(=O)O.C=C(C)C(=O)OC(F)c1ccccc1F

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
ELANE P08246 1/20 0.37
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
GAA P10253 1/20 0.36
CNR2 P34972 1/20 0.35
CYP3A4 P08684 1/20 0.34
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HIF1A Q16665 1/20 0.33
MC4R P32245 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PKM P14618 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7633829 0.95 MEN1 (0.39) MEN1KMT2AELANECES2CES1
Methacrylic Acid SCHEMBL8166195 0.81 HPGD (0.42) KMT2AELANECYP3A4ALDH1A1LMNA
SCHEMBL14648214 0.79 IDO1 (0.50) MEN1KMT2AELANECES2CES1
SCHEMBL27668701 0.79 MEN1 (0.49) MEN1KMT2ACES2CES1GAA
SCHEMBL527905 0.78 HPGD (0.44) KMT2AELANECES2CES1CYP3A4
SCHEMBL4606754 0.72 CES2 (0.40) MEN1KMT2ACES2CES1GAA
SCHEMBL962438 0.69 HPGD (0.50) MEN1KMT2AELANECES2CES1
SCHEMBL1131746 0.69 ESR1 (0.49) KMT2AELANECYP3A4ALDH1A1LMNA
Methacrylic Acid SCHEMBL25394729 0.68 MTNR1A (0.43) MEN1KMT2AELANEGAAALDH1A1
Hydrochloric Acid SCHEMBL3407685 0.68 GAA (0.42) MEN1KMT2ACES2CES1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0878503-B1 RUBBER COMPOSITION LOWERED IN HEAT BUILD-UP AND ROLLS NIPPON ZEON CO (JP) 2003-12-17 EP disclosed
EP-0878503-A1 RUBBER COMPOSITION LOWERED IN HEAT BUILD-UP AND ROLLS NIPPON ZEON CO., LTD. (JP) 1998-11-18 EP disclosed