Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.32 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571291 | 0.82 | TRPA1 (0.43) | TRPA1TRPM8EPHX2GABRR1GABRR2 | |
| SCHEMBL805178 | 0.81 | TRPA1 (0.41) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL3479924 | 0.79 | TRPA1 (0.40) | TRPA1TRPM8EPHX2CA1CA2 | |
| SCHEMBL12166555 | 0.79 | TRPA1 (0.40) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL13916212 | 0.79 | TRPA1 (0.40) | TRPA1TRPM8EPHX2CA1CA2 | |
| SCHEMBL12413525 | 0.78 | TRPA1 (0.36) | TRPA1TRPM8 | |
| SCHEMBL12077578 | 0.78 | TRPA1 (0.33) | TRPA1TRPM8EPHX2GABRR1GABRR2 | |
| SCHEMBL3539422 | 0.76 | EPHX2 (0.32) | EPHX2GABRR1GABRR2 | |
| SCHEMBL12166561 | 0.76 | CA1 (0.54) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL22482026 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168380-A1 | PROCESS FOR SYNTHESIZING CYCLIC PEPTIDE COMPOUND | THE UNIVERSITY OF TOKYO (JP) | 2010-07-01 | — | — | US | disclosed |
| EP-0866052-B1 | Process for the preparation of 1-amino-1-methyl-3(4)-aminomethylcyclohexane | BAYER AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| US-4835239-A | Diisocyanates and their use for the preparation of polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | disclosed |
| EP-0193828-B1 | POLYISOCYANATES CONTAINING ISOCYANURATE GROUPS, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ISOCYANATE COMPONENTS IN THE PRODUCTION OF POLYURETHANE LACQUERS | BAYER AG (DE) | 1988-04-27 | — | — | EP | disclosed |
| EP-0153561-B1 | DIISOCYANATES AND THEIR USE IN THE PRODUCTION OF POLYURETHANE PLASTICS | BAYER AG (DE) | 1987-08-12 | — | — | EP | disclosed |
| US-4613685-A | Aliphatic-cycloaliphatic diisocyanates | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-23 | — | — | US | disclosed |
| EP-0193828-A1 | Polyisocyanates containing isocyanurate groups, process for their production and their use as isocyanate components in the production of polyurethane lacquers | BAYER AG (DE) | 1986-09-10 | — | — | EP | disclosed |
| EP-0153561-A1 | Diisocyanates and their use in the production of polyurethane plastics | BAYER AG (DE) | 1985-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168380-A1 | PROCESS FOR SYNTHESIZING CYCLIC PEPTIDE COMPOUND | VIP, NGLY1, QPCT | TRPA1 3810/4885TRPM8 3152/4885EPHX2 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.