Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805178 | 0.83 | TRPA1 (0.41) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL12166561 | 0.82 | CA1 (0.54) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL3479924 | 0.81 | TRPA1 (0.40) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL13916212 | 0.81 | TRPA1 (0.40) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL12159671 | 0.81 | TRPA1 (0.45) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL3249131 | 0.81 | TRPA1 (0.45) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL31516173 | 0.81 | TRPA1 (0.45) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL18644147 | 0.81 | TRPA1 (0.45) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL24920330 | 0.80 | — | — | |
| SCHEMBL13924883 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428990-A | Plasticizer composition comprising polymerization dicarboxylic ester and dimethyl terephthalate ester | 巴斯夫欧洲公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-104822648-B | Preparation has the method for the cyclohexane-carboxylic acid derivatives of low ratio by-product | 巴斯夫欧洲公司 | 2016-11-09 | — | — | CN | disclosed |
| WO-2016100281-A1 | INDOLE AND AZAINDOLES DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES | MERCK PATENT GMBH (DE) | 2016-06-23 | — | — | WO | disclosed |
| US-20160168090-A1 | NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES | MERCK PATENT GMBH (DE) | 2016-06-16 | — | — | US | disclosed |
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9012497-B2 | Cyclohexyl carbamate compounds as active anti-cellulite ingredients | SYMRISE AG (DE) | 2015-04-21 | — | — | US | disclosed |
| US-9012497-B2 | Cyclohexyl carbamate compounds as active anti-cellulite ingredients | SYMRISE AG (DE) | 2015-04-21 | — | — | US | disclosed |
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | SYMRISE AG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-20130137710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE AG (DE) | 2013-05-30 | — | — | US | disclosed |
| US-20130137710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE AG (DE) | 2013-05-30 | — | — | US | disclosed |
| EP-2389922-A1 | Cyclohexyl carbamate compounds as anti-ageing actives | Symrise AG (DE) | 2011-11-30 | — | — | EP | disclosed |
| CN-100446747-C | Cosmetic compositions comprising cyclohexanepolycarboxylic acid derivatives | BASF AG (DE) | 2008-12-31 | — | — | CN | disclosed |
| CN-1784203-A | Cosmetic composition containing cyclohexane polycarboxylic acid derivative | BASF AG (DE) | 2006-06-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168090-A1 | NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES | P2RX3, P2RX7, P2RX2 | TRPA1 71/4885TRPM8 133/4885CA1 2719/4885 |
| US-20130156710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS SKIN AND/OR HAIR LIGHTENING ACTIVES | CBR1, CYP2A13, CBR3 | TRPA1 304/4885TRPM8 1735/4885CA1 2601/4885 |
| US-20130137710-A1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | CBR1, NCOR2, CECR2 | TRPA1 462/4885TRPM8 2152/4885CA1 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.