Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634078 | 1.00 | KMT2A (0.40) | KMT2APRKDCGPR35AKR1B1MAOB | |
| SCHEMBL7634359 | 0.90 | PRKDC (0.41) | KMT2APRKDCGPR35CYSLTR2CYSLTR1 | |
| SCHEMBL7634364 | 0.90 | PRKDC (0.41) | KMT2APRKDCGPR35CYSLTR2CYSLTR1 | |
| SCHEMBL7626681 | 0.90 | PRKDC (0.40) | KMT2APRKDCLMNAKDM4EHPGD | |
| SCHEMBL7626670 | 0.90 | PRKDC (0.40) | KMT2APRKDCLMNAKDM4EHPGD | |
| SCHEMBL7636912 | 0.85 | PRKDC (0.39) | KMT2APRKDCLMNAPTPN1KDM4E | |
| SCHEMBL7630341 | 0.84 | PRKDC (0.41) | KMT2APRKDCLMNA | |
| SCHEMBL7630340 | 0.84 | PRKDC (0.41) | KMT2APRKDCLMNA | |
| SCHEMBL7630922 | 0.82 | GPR35 (0.49) | KMT2AGPR35TP53THRBLMNA | |
| SCHEMBL7633117 | 0.80 | PRKDC (0.37) | PRKDCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-B1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2002-06-12 | — | — | EP | disclosed |
| US-5990142-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS HAVING GOOD ORAL ADSORPTION AND BIOAVAILABILITY; CARDIOTONIC AND ANTIISCHEMIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1999-11-23 | — | — | US | disclosed |