Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12980401 | 0.85 | NAAA (0.60) | NPSR1NAAAHPGDTRPV1ALDH1A1 | |
| SCHEMBL10038330 | 0.85 | NAAA (0.60) | NPSR1NAAAHPGDTRPV1ALDH1A1 | |
| SCHEMBL31047588 | 0.84 | CA12 (0.67) | NPSR1HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL31047581 | 0.84 | CA12 (0.67) | NPSR1HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10717943 | 0.84 | CA12 (0.67) | NPSR1HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9059823 | 0.84 | CA12 (0.67) | NPSR1HPGDALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27975503 | 0.84 | CA12 (0.52) | NPSR1NAAAHPGDTRPV1ALDH1A1 | |
| SCHEMBL3993600 | 0.81 | NPSR1 (0.79) | NPSR1 | |
| SCHEMBL22275899 | 0.81 | TRPV1 (0.70) | HPGDTRPV1ALDH1A1EPHX2 | |
| SCHEMBL4585892 | 0.80 | TRPV1 (0.73) | NAAAHPGDTRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911320-B1 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-6114325-A | 1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| CN-1224712-A | 1,2-Di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO LTD (JP) | 1999-08-04 | — | — | CN | disclosed |
| EP-0911320-A2 | 1,2-Di-substituted benzenecarboxamide derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 1999-04-28 | — | — | EP | disclosed |