Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 17/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627987 | 0.92 | GPR35 (0.47) | GPR35TP53THRBRAB9AGPR55 | |
| SCHEMBL7633772 | 0.91 | GPR35 (0.55) | GPR35GPR55 | |
| SCHEMBL7628831 | 0.85 | GPR35 (0.46) | GPR35TP53THRBGPR55 | |
| SCHEMBL7632378 | 0.82 | GPR35 (0.58) | GPR35GPR55 | |
| SCHEMBL7628839 | 0.81 | GPR35 (0.47) | GPR35TP53THRBRAB9AGPR55 | |
| SCHEMBL7632427 | 0.81 | GPR35 (0.46) | GPR35TP53THRBRAB9AGPR55 | |
| SCHEMBL7626486 | 0.81 | GPR35 (0.49) | GPR35GPR55 | |
| SCHEMBL7633188 | 0.80 | GPR35 (0.44) | GPR35GPR55 | |
| SCHEMBL7636724 | 0.80 | GPR35 (0.41) | GPR35GPR55 | |
| SCHEMBL7630922 | 0.79 | GPR35 (0.49) | GPR35TP53THRBRAB9AGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-B1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2002-06-12 | — | — | EP | disclosed |
| US-5990142-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS HAVING GOOD ORAL ADSORPTION AND BIOAVAILABILITY; CARDIOTONIC AND ANTIISCHEMIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1999-11-23 | — | — | US | disclosed |