Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 14/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7633128 | 0.90 | GPR35 (0.51) | GPR35CYSLTR2CYSLTR1GPR55 | |
| SCHEMBL7629736 | 0.88 | GPR35 (0.41) | GPR35MEN1KMT2AL3MBTL1MTNR1A | |
| SCHEMBL7627987 | 0.88 | GPR35 (0.47) | GPR35CYSLTR2CYSLTR1GPR55 | |
| SCHEMBL7633188 | 0.86 | GPR35 (0.44) | GPR35CYSLTR2CYSLTR1GPR55 | |
| SCHEMBL7628831 | 0.81 | GPR35 (0.46) | GPR35CYSLTR2CYSLTR1GPR55 | |
| SCHEMBL7634210 | 0.80 | GPR35 (0.57) | GPR35GPR55 | |
| SCHEMBL7631251 | 0.78 | GPR35 (0.51) | GPR35CYSLTR2CYSLTR1GPR55 | |
| SCHEMBL7626734 | 0.78 | MTNR1A (0.40) | MTNR1AMTNR1BPPARG | |
| SCHEMBL7632378 | 0.77 | GPR35 (0.58) | GPR35CYSLTR2CYSLTR1GPR55 | |
| SCHEMBL7628839 | 0.77 | GPR35 (0.47) | GPR35MEN1KMT2AL3MBTL1GPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-B1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2002-06-12 | — | — | EP | disclosed |
| US-5990142-A | ANTIINFLAMMATORY AGENTS AND ANTIALLERGENS HAVING GOOD ORAL ADSORPTION AND BIOAVAILABILITY; CARDIOTONIC AND ANTIISCHEMIC AGENTS | LABORATORIOS MENARINI S.A. (ES) | 1999-11-23 | — | — | US | disclosed |