Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | ADAM10 | O14672 | 3/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5667630 | 0.98 | KMO (0.49) | HDAC4HDAC2HDAC8KMOHTR2C | |
| SCHEMBL15566600 | 0.92 | HTR2C (0.43) | HDAC4HDAC2HDAC8KMOHTR2C | |
| SCHEMBL6388862 | 0.85 | ESR2 (0.43) | HDAC4HDAC2HDAC8HTR2CADAM10 | |
| SCHEMBL16957285 | 0.85 | HDAC4 (0.45) | HDAC4HDAC2HDAC8KMOHTR2C | |
| SCHEMBL12278164 | 0.84 | HTR2C (0.62) | HTR2C | |
| SCHEMBL1364527 | 0.84 | HTR2C (0.38) | HDAC4HDAC2HDAC8HTR2CADAM10 | |
| SCHEMBL5669789 | 0.84 | HTR2C (0.38) | HDAC4HDAC2HDAC8HTR2CADAM10 | |
| SCHEMBL19633776 | 0.84 | SOS1 (0.46) | HDAC4HDAC2HDAC8HTR2CADAM10 | |
| SCHEMBL19730617 | 0.83 | DRD2 (0.57) | HTR2CDRD2DRD3 | |
| SCHEMBL5670741 | 0.82 | ESR2 (0.43) | HDAC4HDAC2HDAC8HTR2CADAM10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1250365-A2 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS | Basell Polypropylen GmbH (DE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001048034-A2 | TRANSITION METAL COMPOUND, LIGAND SYSTEM, CATALYST SYSTEM AND THE USE OF THE LATTER FOR THE POLYMERISATION AND COPOLYMERISATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2001-07-05 | — | — | WO | disclosed |