Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7485321 | 0.98 | CYP1A2 (0.53) | CYP1A2XDHMAPTKDM4EMAPK1 | |
| SCHEMBL13330085 | 0.81 | ALDH1A1 (0.50) | CYP1A2MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL6802319 | 0.80 | CYP1A2 (0.53) | CYP1A2XDHMAPTKDM4EMAPK1 | |
| SCHEMBL20645712 | 0.77 | CYP1A2 (0.50) | CYP1A2XDHMAPTKDM4EMAPK1 | |
| SCHEMBL17130065 | 0.77 | XDH (0.57) | CYP1A2XDHMAPTKDM4EMAPK1 | |
| SCHEMBL20159041 | 0.74 | CYP1A2 (0.47) | CYP1A2XDHMAPTKDM4EMAPK1 | |
| SCHEMBL16416120 | 0.73 | CYP1A2 (0.46) | CYP1A2XDHMAPTKDM4EMAPK1 | |
| SCHEMBL9918749 | 0.72 | CYP1A2 (0.49) | CYP1A2XDHMAPTKDM4EMAPK1 | |
| SCHEMBL15865616 | 0.71 | CYP1A2 (0.62) | CYP1A2XDHMAPTKDM4EMAPK1 | |
| SCHEMBL28618724 | 0.71 | CYP1A2 (0.52) | CYP1A2XDHMAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173223-A2 | CONJUGATES AS THERAPIES FOR CANCERS AND PROSTATE DISEASES | Slil Biomedical Corporation (US) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066175-A2 | CONJUGATES AS THERAPIES FOR CANCER AND PROSTATE DISEASES | SLIL BIOMEDICAL CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |