SCHEMBL7634368

SCHEMBL7634368

C=C[Si](C=C)(CC)c1ccc(C(=O)OO[C]2CCC(C)CC2C)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7625169 0.89 NPC1 (0.30) NPC1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL7626831 0.86 NPC1 (0.36) NPC1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL7634533 0.86
SCHEMBL7627429 0.86 NR1H2 (0.32)
SCHEMBL7624024 0.84 RAB9A (0.32) NPC1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL7635515 0.84 NPC1 (0.30) NPC1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL7627888 0.82 ALDH1A1 (0.31) ALDH1A1MAPTSMN1; SMN2
SCHEMBL7636940 0.81 MAPT (0.34) NPC1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL7627663 0.81 MEN1 (0.40) NPC1ALDH1A1MAPTRAB9ASMN1; SMN2
SCHEMBL7627868 0.80 RAB9A (0.38) NPC1ALDH1A1MAPTRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed