Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 5/20 | 0.56 |
| ▸ | CTSA | P10619 | 4/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4927517 | 0.89 | JAK2 (0.46) | CYP26A1JAK2ALDH1A1LMNAPKM | |
| SCHEMBL4597215 | 0.87 | JAK2 (0.45) | CYP26A1JAK2ALDH1A1LMNAPKM | |
| SCHEMBL16805929 | 0.87 | JAK2 (0.45) | CYP26A1JAK2ALDH1A1LMNAPKM | |
| SCHEMBL348499 | 0.86 | CTSK (0.54) | CYP26A1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL348500 | 0.86 | CTSK (0.54) | CYP26A1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL46367 | 0.86 | CTSK (0.54) | CYP26A1KMT2ANPSR1CTSKCTSS | |
| SCHEMBL16293719 | 0.86 | CTSK (0.44) | CYP26A1CTSKCTSS | |
| SCHEMBL10311378 | 0.86 | CTSK (0.44) | CYP26A1CTSKCTSS | |
| SCHEMBL6259288 | 0.86 | CYP26A1 (0.57) | CYP26A1CTSAJAK2ALDH1A1LMNA | |
| SCHEMBL22690656 | 0.86 | CTSK (0.50) | CYP26A1CTSAALDH1A1CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |