SCHEMBL7634754

SCHEMBL7634754

C1=CC([Hf](c2ccccc2)(c2ccccc2)(C2C=Cc3ccccc32)[SiH](c2ccccc2)c2ccccc2)c2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7629863 0.82 SIGMAR1 (0.32) HTR6HTR2A
SCHEMBL217386 0.79 HTR6 (0.31) HTR6HTR2A
SCHEMBL7634063 0.79 SIGMAR1 (0.32) HTR6HTR2A
SCHEMBL1130631 0.79 HTR6 (0.31) HTR6HTR2A
SCHEMBL7629879 0.78 SIGMAR1 (0.34) HTR6HTR2A
SCHEMBL7638143 0.74 SIGMAR1 (0.35) HTR6HTR2A
SCHEMBL216943 0.73 SIGMAR1 (0.31)
SCHEMBL3385860 0.73 HTR6 (0.33) HTR6HTR2A
SCHEMBL3382399 0.73 HTR6 (0.33) HTR6HTR2A
SCHEMBL3383074 0.73 HTR6 (0.33) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849288-B1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORP (JP) 2002-11-27 EP disclosed
US-5906955-A Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1999-05-25 US disclosed
EP-0849288-A1 Catalyst for polymerization of an olefin, and method for producing an olefin polymer TOSOH CORPORATION (JP) 1998-06-24 EP disclosed