Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 10/20 | 0.61 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30120525 | 0.98 | BDKRB2 (0.62) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 | |
| Iodide SCHEMBL7630309 | 0.97 | BDKRB2 (0.61) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL548534 | 0.97 | BDKRB2 (0.66) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 | |
| Bromide SCHEMBL7627895 | 0.93 | BDKRB2 (0.65) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 | |
| Bromide SCHEMBL7635711 | 0.93 | BDKRB2 (0.65) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 | |
| SCHEMBL27200564 | 0.92 | BDKRB2 (0.56) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 | |
| SCHEMBL30901612 | 0.92 | BDKRB2 (0.62) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL2208229 | 0.90 | BDKRB2 (0.65) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 | |
| Iodide SCHEMBL7630057 | 0.90 | BDKRB2 (0.60) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL6389237 | 0.90 | BDKRB2 (0.65) | BDKRB2TAS1R3TAS1R1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945141-B1 | Use of a liquid for disinfecting contact lenses | MENICON CO LTD (JP) | 2002-07-24 | — | — | EP | disclosed |
| US-20010055603-A1 | WATER-SOLUBLE ANTIBACTERIAL POLYMER AND LIQUID FORMULATION COMPRISING IT FOR CONTACT LENSES | MENICON CO., LTD. (JP) | 2001-12-27 | — | — | US | disclosed |
| US-20010016190-A1 | Water -soluble antibacterial polymer and liquid formulation comprising it for contact lenses | MENICON CO., LTD. (JP) | 2001-08-23 | — | — | US | disclosed |
| US-6160069-A | Liquid for contact lenses | MENICON, CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-0947856-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1999-10-06 | — | — | EP | disclosed |
| EP-0945141-A2 | Liquid for contact lenses | Menicon Co., Ltd. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0916682-A1 | Water-soluble antibacterial polymer and liquid formulation comprising it for contact lenses | Menicon Co., Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010016190-A1 | Water -soluble antibacterial polymer and liquid formulation comprising it for contact lenses | ARGLU1, H1-0, H1-2 | BDKRB2 4844/4885TAS1R3 593/4885TAS1R1 189/4885 |
| US-20010055603-A1 | WATER-SOLUBLE ANTIBACTERIAL POLYMER AND LIQUID FORMULATION COMPRISING IT FOR CONTACT LENSES | ARGLU1, H1-0, H1-2 | BDKRB2 4844/4885TAS1R3 593/4885TAS1R1 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.