SCHEMBL7634855

SCHEMBL7634855

CN1C(=O)SC(=O)C1c1ccc2cc(OCc3c(F)cccc3F)ccc2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ANO1 Q5XXA6 3/20 0.36
ALKBH1 Q13686 1/20 0.33
ALDH1A1 P00352 3/20 0.33
MAOB P27338 2/20 0.33
MAOA P21397 1/20 0.33
PTPN1 P18031 1/20 0.33
HPGD P15428 2/20 0.32
HPN P05981 1/20 0.32
KDM4E B2RXH2 2/20 0.32
LMNA P02545 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
GABRA5 P31644 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7630998 0.91 GABRG2 (0.34) ALDH1A1MAOBMAOAHPNKDM4E
SCHEMBL7635956 0.88 PTPN1 (0.45) ARMAOBPTPN1SMN1; SMN2
SCHEMBL7634108 0.87 KMT2A (0.38) ARMEN1KMT2AALDH1A1MAOB
SCHEMBL7634857 0.78 AR (0.37) ARMEN1KMT2AANO1ALDH1A1
SCHEMBL7637090 0.77 NR4A2 (0.42) MEN1KMT2APTPN1HPGDPOLB
SCHEMBL3969790 0.67 PARP15 (0.44) ARMAOBPTPN1SMN1; SMN2
SCHEMBL8877885 0.66 PARP15 (0.43) ARMAOBPTPN1SMN1; SMN2
SCHEMBL8877887 0.66 PARP15 (0.43) ARMAOBPTPN1SMN1; SMN2
SCHEMBL7634109 0.65 KMT2A (0.38) ARMEN1KMT2AALDH1A1MAOB
SCHEMBL7634850 0.64 FFAR1 (0.57) ALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1186588-A1 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2002-03-13 EP disclosed