Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630631 | 0.95 | TDP1 (0.48) | DGKAMMP1MMP2MMP9MMP12 | |
| SCHEMBL7631237 | 0.89 | MMP1 (0.48) | MMP1MMP2MMP9MMP12TDP1 | |
| SCHEMBL1709751 | 0.82 | MMP1 (0.50) | MMP1MMP2MMP9MMP12TDP1 | |
| SCHEMBL9803080 | 0.79 | DGKA (0.56) | DGKAPAMELANETSHRMAPT | |
| SCHEMBL17938462 | 0.78 | CYP4F2 (0.46) | DGKATDP1PAMELANEL3MBTL1 | |
| SCHEMBL17938487 | 0.77 | CYP4F2 (0.54) | DGKATDP1PAMELANEL3MBTL1 | |
| SCHEMBL17938432 | 0.77 | DGKA (0.46) | DGKATDP1PAMELANETSHR | |
| SCHEMBL17938466 | 0.77 | DGKA (0.46) | DGKATDP1PAMELANETSHR | |
| SCHEMBL30786801 | 0.76 | DGKA (0.53) | DGKAPAMELANEEPHX2 | |
| SCHEMBL30786800 | 0.76 | DGKA (0.53) | DGKAPAMELANEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6452056-B1 | REDUCING FLUORINATED BENZONITRILE TO A BENZYLAMINE WHICH IS REPLACED WITH A HYDROXYL GROUP | ASAHI GLASS COMPANY, LIMITED (JP) | 2002-09-17 | — | — | US | disclosed |
| EP-1114809-A1 | PROCESS FOR THE PREPARATION OF FLUOROBENZYL DERIVATIVES | Asahi Glass Co., Ltd. (JP) | 2001-07-11 | — | — | EP | disclosed |