SCHEMBL7635264

SCHEMBL7635264

O=C1CSC(=O)N1Cc1cccc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.64
GSK3A P49840 1/20 0.58
GSK3B P49841 1/20 0.58
ALDH1A1 P00352 3/20 0.47
MAPT P10636 2/20 0.47
GAA P10253 1/20 0.47
POLB P06746 1/20 0.44
DAO P14920 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HTT P42858 1/20 0.43
ACHE P22303 1/20 0.42
CMA1 P23946 1/20 0.42
CA12 O43570 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
CA9 Q16790 1/20 0.41
PPARG P37231 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14860866 0.83 PIM1 (0.54) PIM1GSK3AGSK3BALDH1A1MAPT
SCHEMBL28554314 0.79 DAO (0.49) MAPTPOLBDAOL3MBTL1HTT
SCHEMBL30990560 0.78 PIM1 (1.00) PIM1GSK3AGSK3BALDH1A1MAPT
SCHEMBL8684936 0.76 PIM1 (0.47) PIM1GSK3AGSK3BALDH1A1POLB
SCHEMBL5745448 0.76 GAA (0.43) PIM1GSK3AGSK3BALDH1A1MAPT
SCHEMBL5464026 0.76 PIM1 (0.60) PIM1GSK3AGSK3BALDH1A1MAPT
SCHEMBL4727354 0.75 PIM1 (0.41) PIM1GSK3AGSK3BALDH1A1MAPT
SCHEMBL21489514 0.75 GSK3A (0.60) PIM1GSK3AGSK3BALDH1A1GAA
SCHEMBL8685237 0.74 PIM1 (0.51) PIM1GSK3AGSK3BALDH1A1MAPT
SCHEMBL8691072 0.74 PIM1 (0.72) PIM1GSK3AGSK3BALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10139768-A None JP disclosed
EP-1186588-A1 6-HYDROXY-2-NAPHTHYLCARBINOL AND PROCESS FOR THE PREPARATION THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2002-03-13 EP disclosed
JP-2001039912-A 6-HYDROXY-2-NAPHTHYLCARBINOL AND ITS PRODUCTION MITSUBISHI CHEMICALS CORP 2001-02-13 JP disclosed
JP-H10139768-A PRODUCTION OF NAPHTHALENE DERIVATIVE MITSUBISHI CHEM CORP 1998-05-26 JP disclosed