Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768086 | 0.81 | HTR1A (0.58) | MEN1KMT2A | |
| SCHEMBL4727354 | 0.76 | PIM1 (0.41) | GAAPIM1ALDH1A1MAPTMEN1 | |
| SCHEMBL7635264 | 0.76 | PIM1 (0.64) | GAAPIM1ALDH1A1MAPTGSK3A | |
| SCHEMBL4861936 | 0.73 | DRD2 (0.54) | GAAALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL5746121 | 0.72 | HTR1A (0.70) | — | |
| SCHEMBL8794788 | 0.72 | HPGD (0.64) | MTNR1ANQO2HPGDLMNACA12 | |
| SCHEMBL16106841 | 0.72 | MTNR1A (0.54) | KMT2AMTNR1ANQO2HPGDCA12 | |
| Hydrochloric Acid SCHEMBL8780119 | 0.71 | SIGMAR1 (0.56) | HSD17B10KDM4EL3MBTL1 | |
| SCHEMBL14544011 | 0.70 | CA12 (0.59) | ALDH1A1KMT2AMTNR1ANQO2HSD17B10 | |
| SCHEMBL4776890 | 0.70 | HTR1A (0.56) | GAAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101172977-A | Novel derivatives of cycloalcanodiones, method for the production thereof and their pharmacological applications | CEPA SCHWARZ PHARMA S L (ES) | 2008-05-07 | — | — | CN | claimed |
| EP-1544201-B1 | NOVEL DERIVATIVES OF CYCLOALCANODIONES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACOLOGICAL APPLICATIONS | CEPA SCHWARZ PHARMA S L (ES) | 2006-06-28 | — | — | EP | claimed |
| EP-1544201-B1 | NOVEL DERIVATIVES OF CYCLOALCANODIONES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACOLOGICAL APPLICATIONS | CEPA SCHWARZ PHARMA S L (ES) | 2006-06-28 | — | — | EP | disclosed |
| EP-1544201-A1 | NOVEL DERIVATIVES OF CYCLOALCANODIONES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACOLOGICAL APPLICATIONS | Cepa Schwarz Pharma s.l. (ES) | 2005-06-22 | — | — | EP | disclosed |