Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8687562 | 0.87 | GSK3A (0.50) | PIM1GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL8685285 | 0.76 | PIM1 (0.47) | PIM1GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL8685583 | 0.76 | HTR6 (0.59) | PIM1GSK3AGSK3BHTR6CYP3A4 | |
| SCHEMBL8686737 | 0.75 | PIM1 (0.49) | PIM1GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL8687928 | 0.74 | PIM1 (0.51) | PIM1GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL8691072 | 0.74 | PIM1 (0.72) | PIM1GSK3AGSK3BALDH1A1KMT2A | |
| SCHEMBL8686639 | 0.74 | PIM1 (0.48) | PIM1GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL7635264 | 0.74 | PIM1 (0.64) | PIM1GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL8691044 | 0.74 | GSK3A (0.52) | PIM1GSK3AGSK3BALDH1A1POLB | |
| SCHEMBL8685306 | 0.74 | PIM1 (0.48) | PIM1GSK3AGSK3BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |