SCHEMBL7635274

SCHEMBL7635274

[CH2]OOC(=O)c1ccc(C)cc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
TNF P01375 1/20 0.43
PKM P14618 1/20 0.43
CDK5 Q00535 1/20 0.43
KLF5 Q13887 1/20 0.43
CDK5R1 Q15078 1/20 0.43
NOD1 Q9Y239 1/20 0.43
NFE2L2 Q16236 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TAS1R2 Q8TE23 1/20 0.40
MAPT P10636 1/20 0.40
HSD11B1 P28845 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
NR4A2 P43354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124710 0.88 KMT2A (0.49) KMT2AMEN1RAB9ANPC1TNF
SCHEMBL7633063 0.85 MEN1 (0.46) KMT2AMEN1NPC1SMN1; SMN2MAPT
SCHEMBL4487007 0.85 KMT2A (0.47) KMT2AMEN1RAB9ANPC1TNF
SCHEMBL19256975 0.83 TAS1R3 (0.48) KMT2AMEN1RAB9ANPC1TNF
SCHEMBL7632047 0.81 KMT2A (0.44) KMT2AMEN1RAB9ANPC1TNF
SCHEMBL7628785 0.81 KMT2A (0.45) KMT2AMEN1RAB9ANPC1TNF
SCHEMBL7630929 0.81 NFE2L2 (0.42) KMT2AMEN1RAB9ANPC1TNF
SCHEMBL6113261 0.80 KMT2A (0.49) KMT2AMEN1RAB9ANPC1TNF
SCHEMBL29462647 0.80 KMT2A (0.49) KMT2AMEN1RAB9ANPC1TNF
SCHEMBL7631201 0.80 KMT2A (0.44) KMT2AMEN1RAB9ANPC1TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1233014-A1 ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME NOF CORPORATION (JP) 2002-08-21 EP disclosed