Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343193 | 0.83 | TDP1 (0.67) | TDP1ALDH1A1NCOA1NCOA3VCAM1 | |
| SCHEMBL30694393 | 0.81 | VCAM1 (0.47) | TDP1ALDH1A1VCAM1KDM4DSMN1; SMN2 | |
| SCHEMBL220318 | 0.81 | VCAM1 (0.47) | TDP1ALDH1A1VCAM1KDM4DSMN1; SMN2 | |
| SCHEMBL1341782 | 0.80 | TDP1 (0.55) | TDP1ALDH1A1VCAM1POLBCTSB | |
| SCHEMBL11811062 | 0.79 | TDP1 (0.55) | TDP1ALDH1A1NCOA1NCOA3VCAM1 | |
| SCHEMBL618153 | 0.77 | TDP1 (0.54) | TDP1ALDH1A1VCAM1SMN1; SMN2MEN1 | |
| SCHEMBL57166 | 0.76 | TDP1 (1.00) | TDP1ALDH1A1NCOA1NCOA3SMN1; SMN2 | |
| SCHEMBL29475175 | 0.76 | TDP1 (1.00) | TDP1ALDH1A1NCOA1NCOA3SMN1; SMN2 | |
| SCHEMBL28093598 | 0.74 | TDP1 (0.95) | TDP1ALDH1A1NCOA1NCOA3SMN1; SMN2 | |
| SCHEMBL20690651 | 0.74 | AR (0.42) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763539-B1 | Novel phthalocyanine or naphthalocyanine derivative | ORIENT CHEMICAL IND (JP) | 2002-08-07 | — | — | EP | disclosed |
| US-5739319-A | WATERPROOF DYES | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0763539-A2 | Novel phthalocyanine or naphthalocyanine derivative | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 1997-03-19 | — | — | EP | disclosed |