Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040686 | 1.00 | HTT (0.43) | HTTSMN1; SMN2L3MBTL1SLC13A5TSHR | |
| SCHEMBL6296751 | 0.82 | SLC13A5 (0.43) | SLC13A5CYP2C19HIF1A | |
| SCHEMBL6296754 | 0.82 | SLC13A5 (0.43) | SLC13A5CYP2C19HIF1A | |
| SCHEMBL6693952 | 0.82 | SLC13A5 (0.43) | SLC13A5CYP2C19HIF1A | |
| SCHEMBL7639674 | 0.76 | ALDH1A1 (0.43) | HTTSMN1; SMN2L3MBTL1SLC13A5TSHR | |
| SCHEMBL6296103 | 0.76 | SLC13A5 (0.45) | SLC13A5ALDH1A1KDM4EMAOAHDAC1 | |
| SCHEMBL7635490 | 0.76 | ALDH1A1 (0.43) | HTTSMN1; SMN2L3MBTL1SLC13A5TSHR | |
| SCHEMBL6302904 | 0.76 | SLC13A5 (0.49) | SMN1; SMN2SLC13A5TSHRALDH1A1LMNA | |
| SCHEMBL6695081 | 0.76 | SLC13A5 (0.49) | SMN1; SMN2SLC13A5TSHRALDH1A1LMNA | |
| SCHEMBL6692391 | 0.76 | SLC13A5 (0.49) | SMN1; SMN2SLC13A5TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380400-B1 | DIMETHYLTHIOCARBAMIC ACID ESTER; VIRICIDES | FEDIJ VICTOR (US) | 2002-04-30 | — | — | US | disclosed |
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |