Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639674 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ANPSR1AOC3 | |
| SCHEMBL7999820 | 0.85 | CYP17A1 (0.47) | CA1CA2SLC13A5 | |
| SCHEMBL8041377 | 0.82 | KMT2A (0.47) | ALDH1A1MEN1KMT2ANPSR1KDM4E | |
| SCHEMBL7998721 | 0.81 | SLC13A5 (0.46) | ALDH1A1KDM4ECA2SLC13A5 | |
| SCHEMBL7998719 | 0.81 | SLC13A5 (0.46) | ALDH1A1KDM4ECA2SLC13A5 | |
| SCHEMBL6695081 | 0.81 | SLC13A5 (0.49) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL6302904 | 0.81 | SLC13A5 (0.49) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL6692391 | 0.81 | SLC13A5 (0.49) | ALDH1A1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL7636702 | 0.81 | PPID (0.49) | ALDH1A1MEN1KMT2ANPSR1AOC3 | |
| SCHEMBL7636689 | 0.81 | PPID (0.49) | ALDH1A1MEN1KMT2ANPSR1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | claimed |
| US-6380400-B1 | DIMETHYLTHIOCARBAMIC ACID ESTER; VIRICIDES | FEDIJ VICTOR (US) | 2002-04-30 | — | — | US | disclosed |
| WO-2000015625-A2 | METHODS OF MAKING DIHYDROPYRONE HIV PROTEASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 2000-03-23 | — | — | WO | disclosed |