SCHEMBL7635647

SCHEMBL7635647

C=C(C)C(=O)OCC[Si](CC)(OC(C)=O)OC(C)=O

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.49
TSHR P16473 3/20 0.47
ALDH1A1 P00352 4/20 0.35
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339142 0.84 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL341013 0.83 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL3502490 0.81 TSHR (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL2779024 0.80 THRB (0.48) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL11765241 0.79 TSHR (0.56) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7634908 0.79 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7634931 0.79 THRB (0.47) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7637386 0.77 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7637160 0.77 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL705906 0.77 ALDH1A1 (0.38) TSHRALDH1A1TDP1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101515113-B Radioactive ray sensibility resin composition, interlayer insulating film, microlens and method of forming the same JSR CORP 2012-07-18 CN disclosed
US-6399212-B1 COATINGS WITH ORGANOSILICON COMPOUNDS AND SOLUTION OF SILICOFLUORIC ACID AND SILICON DIOXIDE NIPPON SHEET GLASS CO., LTD. (JP) 2002-06-04 US disclosed
CN-1293216-A Polyolefinic resin for coating silicon dioxide and its preparation method NIPPON SHEET GLASS CO LTD (JP) 2001-05-02 CN disclosed
EP-1094090-A2 Silicon dioxide-coated polyolefin resin and process for its production NIPPON SHEET GLASS CO. LTD. (JP) 2001-04-25 EP disclosed