SCHEMBL7635786

SCHEMBL7635786

CC1=C2CCCCCCCCC2CC1=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.38
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
SRC P12931 2/20 0.33
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
NR1I2 O75469 1/20 0.32
KDM4B O94953 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
DOHH Q9BU89 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CASP1 P29466 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7636283 1.00 KMT2A (0.38) KMT2ACA1CA2CA4SRC
SCHEMBL7633674 1.00 KMT2A (0.38) KMT2ACA1CA2CA4SRC
SCHEMBL7942188 1.00 KMT2A (0.38) KMT2ACA1CA2CA4SRC
SCHEMBL7636295 1.00 KMT2A (0.38) KMT2ACA1CA2CA4SRC
SCHEMBL7636309 1.00 KMT2A (0.38) KMT2ACA1CA2CA4SRC
SCHEMBL7642946 0.98 CA1 (0.35) KMT2ACA1CA2CA4SRC
SCHEMBL7653264 0.92 MAPT (0.34) MAPT
SCHEMBL7640453 0.76 KMT2A (0.34) KMT2ACA1CA2CA4
SCHEMBL7635753 0.76 ALDH1A1 (0.38) KMT2ACA1CA2CA4ALDH1A1
SCHEMBL7636049 0.76 ALDH1A1 (0.38) KMT2ACA1CA2CA4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6482966-B2 REDUCING A CROSSLINK-CYCLIZED CYCLOPENTANONE WITH AN ALKALI METAL HYDRIDE, AND THEN REATING THE RESULTING CROSSLINK-CYCLIZED CYCLOPENTENOL IS WITH A DEHYDRATING AGENT HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2002-11-19 US disclosed
US-20010012902-A1 Crosslink-cyclized cyclopentadiene and dihalobis type metal compound containing same as ligand HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2001-08-09 US disclosed
EP-1122229-A1 Process for the preparation of condensed cyclopentadiene derivatives, 1, 3 disubstituted derivatives and metallocene type compounds containing them as ligand HONSHU CHEMICAL INDUSTRY CO. LTD. (JP) 2001-08-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010012902-A1 Crosslink-cyclized cyclopentadiene and dihalobis type metal compound containing same as ligand CYC1, DCLRE1A, PPIL1 KMT2A 4702/4885CA1 152/4885CA2 558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.