Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17747939 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRDRD1DAPK3JAK2 | |
| SCHEMBL8759106 | 0.80 | ALDH1A1 (0.59) | ALDH1A1TSHRDRD1POLBTDP1 | |
| SCHEMBL28928500 | 0.78 | ALDH1A1 (0.56) | ALDH1A1TSHRDRD1POLBTDP1 | |
| SCHEMBL28017957 | 0.77 | KDM4E (0.37) | ALDH1A1TSHRPOLBFLT3MAPK14 | |
| SCHEMBL585316 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TSHRDRD1POLBDAPK3 | |
| SCHEMBL1115568 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRPOLBABL1FYN | |
| SCHEMBL8349563 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRDRD1 | |
| SCHEMBL20637070 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRDRD1POLBDAPK3 | |
| SCHEMBL8757864 | 0.75 | CYP2A6 (0.58) | ALDH1A1TSHRDRD1JAK2 | |
| SCHEMBL8759331 | 0.75 | ALDH1A1 (0.58) | ALDH1A1TSHRDRD1DAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171481-A1 | SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME | Cryovac, Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6197714-B1 | USEFUL IN SLURRY AND GAS PHASE POLYMERIZATION OF OLEFINS | CRYOVAC, INC. | 2001-03-06 | — | — | US | disclosed |
| WO-2000056786-A1 | SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME | CRYOVAC, INC. (US) | 2000-09-28 | — | — | WO | disclosed |