SCHEMBL8759331

SCHEMBL8759331

C=Cc1ccc(-c2ccccc2Br)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
MAPK1 P28482 4/20 0.58
TSHR P16473 2/20 0.46
RAB9A P51151 4/20 0.37
NPC1 O15118 3/20 0.37
TP53 P04637 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 2/20 0.37
DRD1 P21728 3/20 0.36
NFKB1 P19838 2/20 0.33
NFKB2 Q00653 2/20 0.33
RELA Q04206 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
DAPK3 O43293 1/20 0.33
JAK2 O60674 1/20 0.33
ABL1 P00519 1/20 0.33
NTRK1 P04629 1/20 0.33
FYN P06241 1/20 0.33
CSF1R P07333 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12489603 0.82 ALDH1A1 (0.83) ALDH1A1MAPK1TSHRRAB9ANPC1
SCHEMBL8759106 0.80 ALDH1A1 (0.59) ALDH1A1MAPK1TSHRTP53HPGD
SCHEMBL28802140 0.79 ALDH1A1 (0.58) ALDH1A1MAPK1TSHRRAB9ANPC1
SCHEMBL8176332 0.79 ALDH1A1 (0.58) ALDH1A1MAPK1TSHRRAB9ANPC1
SCHEMBL26127658 0.79 ALDH1A1 (0.52) ALDH1A1MAPK1TSHRRAB9ANPC1
SCHEMBL28928500 0.78 ALDH1A1 (0.56) ALDH1A1MAPK1TSHRTP53HPGD
SCHEMBL585316 0.77 ALDH1A1 (0.48) ALDH1A1TSHRDRD1DAPK3JAK2
SCHEMBL8758537 0.76 ALDH1A1 (0.48) ALDH1A1MAPK1TSHRTP53TDP1
SCHEMBL7635802 0.75 ALDH1A1 (0.46) ALDH1A1TSHRDRD1DAPK3JAK2
SCHEMBL8757864 0.75 CYP2A6 (0.58) ALDH1A1TSHRRAB9ANPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109516923-A Compounds and organic luminescent device comprising it 东进世美肯株式会社 2019-03-26 CN disclosed
EP-0570932-B1 Styrenic block copolymer and process for producing same IDEMITSU KOSAN CO (JP) 1997-07-23 EP disclosed
EP-0559108-B1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN CO (JP) 1997-05-28 EP disclosed
US-5554695-A Styrenic copolymer and process for producing same IDEMITSU KOSAN CO. LTD. (JP) 1996-09-10 US disclosed
EP-0511407-B1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN CO (JP) 1996-05-29 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5475061-A High degree of syndiotactic configuration; using alumoxane and transition metal compound catalysts IDEMITSU KOSAN CO., LTD. (JP) 1995-12-12 US disclosed
EP-0444210-B1 ARYLSTYRENE POLYMER AND COPOLYMER AND PROCESS FOR PREPARING THE SAME IDEMITSU KOSAN CO (JP) 1995-05-24 EP disclosed
US-5418276-A Styrene copolymer, syndiotactic, heat resistance, chemical resistance IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5418290-A Compatability with other resins, adhesion IDEMITSU KOSAN CO., LTD. (JP) 1995-05-23 US disclosed
US-5403908-A Aryl styrene-based copolymer IDEMITSU KOSAN COMPANY, LIMITED (JP) 1995-04-04 US disclosed
US-5391626-A Syndiotactic, high performance, compatibility and adhesiveness; molding materials IDEMITSU KOSAN CO., LTD. (JP) 1995-02-21 US disclosed
US-5362814-A Styrene polymers with olefin monomers and diolefin monomers for impact strength in molding materials IDEMITSU KOSAN CO., LTD. (JP) 1994-11-08 US disclosed
EP-0570931-A2 Styrenic polymer, process for producing same and multi-layer material comprising same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
EP-0570932-A2 Styrenic block copolymer and process for producing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
EP-0559108-A1 Graft copolymer, process for production thereof and resin composition containing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-08 EP disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed
EP-0444210-A1 ARYLSTYRENE POLYMER AND COPOLYMER AND PROCESS FOR PREPARING THE SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-09-04 EP disclosed
US-3974094-A COMPOUND, 6B, ORGANOALUMINUM COMPOUND, VINYLIC HALIDE CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed